Glucosamine
UK guidance for osteoarthritis does not recommend glucosamine, because trials have not shown a clear benefit.
Short answer UK guidance for osteoarthritis does not recommend glucosamine, because trials have not shown a clear benefit. Exercise and weight management have the better evidence.
Cautions
Usually made from shellfish. It can interact with warfarin and may affect blood sugar.
If joints are the concern
See a GP or physiotherapist. Our page on collagen for joints covers that evidence.
Related pages
- MelatoninIn the UK melatonin is a prescription-only medicine, not a food supplement.
- AshwagandhaAshwagandha is a herb used in Ayurvedic tradition.
- Turmeric and curcuminCurcumin, from turmeric, has no authorised health claim.
- Lion's mane mushroomLion's mane is an edible mushroom sold for memory and focus.
Keep exploring
- Prebiotics
- Berberine
- How to choose the best collagen supplement
- Pregnancy vitamins and supplements
- Supplement safety
- When and how to take collagen
Questions people ask
What should I know about glucosamine?
UK guidance for osteoarthritis does not recommend glucosamine, because trials have not shown a clear benefit.
Can I take this with medication?
Ask a pharmacist or GP first; some supplements interact with medicines.
Do supplements replace a balanced diet?
No. They are meant to add to a varied diet, not stand in for one.
Sources
Checked 9 October 2026.