Berberine
Berberine is a plant compound studied for blood sugar and cholesterol.
Short answer Berberine is a plant compound studied for blood sugar and cholesterol. It is not a weight loss treatment and is not a substitute for prescribed medicine. It commonly causes stomach upset.
Interactions
With metformin and other diabetes medicines, ciclosporin and several others. Do not take it in pregnancy or while breastfeeding.
Our view
This is one to discuss with a GP or pharmacist first, not to self-prescribe.
Related pages
- NMN and NAD supplementsNMN is a compound the body uses to make NAD, which declines with age.
- Cod liver oilCod liver oil provides omega-3 plus vitamins A and D.
- Evening primrose oilEvening primrose oil contains the omega-6 fat GLA.
- GlucosamineUK guidance for osteoarthritis does not recommend glucosamine, because trials have not shown a clear benefit.
Keep exploring
- When and how to take collagen
- Vitamins for over 50s
- Turmeric and curcumin
- Collagen peptides
- Hair, skin and nail vitamins
- Guides
Questions people ask
What should I know about berberine?
Berberine is a plant compound studied for blood sugar and cholesterol.
Can I take this with medication?
Ask a pharmacist or GP first; some supplements interact with medicines.
Do supplements replace a balanced diet?
No. They are meant to add to a varied diet, not stand in for one.
Sources
Checked 9 October 2026.