Collagen types 1, 2 and 3

Type I is the main collagen in skin, bone and tendon; type II is in cartilage; type III sits alongside type I in skin and blood vessels.

By the Supplements UK editorial team. Last checked 9 October 2026. General information, not medical advice.

Short answer Type I is the main collagen in skin, bone and tendon; type II is in cartilage; type III sits alongside type I in skin and blood vessels. Once hydrolysed and digested, all are broken into similar amino acids and peptides.

Does the type matter?

For hydrolysed collagen, less than labels suggest. The exception is undenatured type II collagen, taken in small doses for joints, which is thought to act differently.

Multi-collagen blends

Offer several types in one product. There is no evidence that more types means more benefit.

Keep exploring

Questions people ask

What should I know about collagen types 1, 2 and 3?

Type I is the main collagen in skin, bone and tendon; type II is in cartilage; type III sits alongside type I in skin and blood vessels.

Can I take this with medication?

Ask a pharmacist or GP first; some supplements interact with medicines.

Do supplements replace a balanced diet?

No. They are meant to add to a varied diet, not stand in for one.

Sources

Checked 9 October 2026.